Entropy:
A key measurement for
personalized anesthesia

Intraoperative awareness facts

26,000 cases

of intraoperative awareness in the U.S. per year and 400,000 globally¹

Experience of awareness with explicit recall of surgical events can potentially lead to post-traumatic stress disorder (PTSD)²

Entropy to assess depth of anesthesia

Entropy use is associated with a 30% reduction in Sevoflurane/ Isoflurane and a 15% reduction in Propofol 4,5,6

Studies have shown that when caring for adults, using Entropy may help hospitals…

Avoid UNDER and OVER dosing

Entropy may help anesthesiologists assess the effect of certain anesthetics on the patient’s brain³

Accelerate recovery & discharge

Entropy may result in faster emergence from anesthesia and may help clinicians in their goal to increase patient throughput⁴

Decrease drug consumption

Entropy may help save hospitals’ money and support an environmentally conscious anaesthesia⁵

Improve hemodynamic stability

Multiple randomized controlled outcome studies report significant reduction in hemodynamic fluctuations, especially avoidance of hypotension 6,7

Sebel PS, Bowdle TA, Ghoneim MM, et al. The incidence of awareness during anesthesia: a multicenter United States study. Anesth Analg. 2004;99(3):833–839. DOI: 10.1213/01.ANE.0000130261.90896.6C. Accessed May 20, 2019.

Mashour GA, Avidan MS. Intraoperative awareness: controversies and non-controversies. Br J Anaesth. 2015;115(Suppl 1):i20–i26. DOI: 10.1093/bja/aev034. Accessed May 20, 2019.

Optimised Anaesthesia to Reduce Post Operative Cognitive Decline (POCD) in Older Patients Undergoing Elective Surgery, a Randomised Controlled Trial, Clive Ballard, Emma Jones, Nathan Gauge, Dag Aarsland, Odd Bjarte Nilsen, Brian K. Saxby, David Lowery, Anne Corbett, Keith Wesnes, Eirini Katsaiti, James Arden, Derek Amaoko, Nicholas Prophet, Balaji Purushothaman, and David Green, published online 2012 Jun 15

Spectral Entropy Monitoring Is Associated with Reduced Propofol Use and Faster Emergence in Propofol–Nitrous Oxide–Alfentanil Anesthesia, Anne Vakkuri, M.D., Ph.D.; Arvi Yli-Hankala, M.D., Ph.D.; Rolf Sandin, M.D., Ph.D.; Seppo Mustola, M.D., Ph.D.; Siv Høymork, M.D.; Stina Nyblom, M.D., Ph.D.; Pia Talja, M.Sc.; Timothy Sampson, M.Sc.; Mark van Gils, Ph.D.; Hanna Viertiö-Oja, Ph.D., August 2005

Aimé I, Verroust N, Masson-Lefoll C, Taylor G, Laloë PA, Liu N, Fischler M. Does monitoring bispectral index or spectral entropy reduce sevoflurane use? Anesth Analg. 2006 Dec;103(6):1469-77.
doi: 10.1213/01.ane.0000246838.93153.23. PMID: 17122226.

El Hor T, Van Der Linden P, De Hert S, Mélot C, Bidgoli J. Impact of entropy monitoring on volatile anesthetic uptake. Anesthesiology. 2013 Apr;118(4):868-73. doi: 10.1097/ALN.0b013e3182850c36. PMID: 23337606.

Gruenewald M, Zhou J, Schloemerkemper N, Meybohm P, Weiler N, Tonner PH, Scholz J, Bein B. M-Entropy guidance vs standard practice during propofol-remifentanil anaesthesia: a randomised controlled trial. Anaesthesia. 2007 Dec;62(12):1224-9. doi: 10.1111/j.1365-2044.2007.05252.x. PMID: 17991257.

Not all products or features are available in all markets. Full product technical specification is available upon request. Contact a GE HealthCare Representative for more information.
Please visit www.gehealthcare.com.
Data subject to change.
© 2024 GE HealthCare
GE is a trademark of General Electric Company used under trademark license. All other trademarks are property of their respective owners.
Reproduction in any form is forbidden without prior written permission from GE HealthCare. Nothing in this material should be used to diagnose or treat any disease or condition. Readers must consult a healthcare professional.

JB06875XX-1 03/2024

Entropy:
A key measurement for personalized anesthesia

Intraoperative awareness facts

26,000 cases

of intraoperative awareness in the U.S. per year
and 400,000 globally¹

Experience of awareness with explicit recall of surgical events can potentially lead to post-traumatic stress disorder (PTSD)²

Entropy to assess depth of anesthesia

Entropy use is associated with a 30% reduction in Sevoflurane/ Isoflurane and a 15% reduction in Propofol 4,5,6

Studies have shown that when caring for adults, using Entropy may help hospitals…

Avoid UNDER and OVER dosing

Entropy may help anesthesiologists assess the effect of certain anesthetics on the patient’s brain³

Accelerate recovery & discharge

Entropy may result in faster emergence from anesthesia and may help clinicians in their goal to increase patient throughput⁴

Decrease drug consumption

Entropy may help save hospitals’ money and support an environmentally conscious anaesthesia⁵

Improve hemodynamic stability

Multiple randomized controlled outcome studies report significant reduction in hemodynamic fluctuations, especially avoidance of hypotension 6,7

Sebel PS, Bowdle TA, Ghoneim MM, et al. The incidence of awareness during anesthesia: a multicenter United States study. Anesth Analg. 2004;99(3):833–839.
DOI: 10.1213/01.ANE.0000130261.90896.6C. Accessed May 20, 2019.

Mashour GA, Avidan MS. Intraoperative awareness: controversies and non-controversies. Br J Anaesth. 2015;115(Suppl 1):i20–i26. DOI: 10.1093/bja/aev034. Accessed May 20, 2019.

Entropy:
A key measurement for personalized anesthesia

Intraoperative awareness facts

26,000 cases

of intraoperative awareness in the U.S. per year and 400,000 globally¹

Experience of awareness with explicit recall of surgical events can potentially lead to post-traumatic stress disorder (PTSD)²

Entropy to assess depth of anesthesia

Entropy use is associated with a 30% reduction in Sevoflurane/ Isoflurane and a 15% reduction in Propofol 4,5,6

Studies have shown that when caring for adults, using Entropy may help hospitals…

Avoid UNDER and OVER dosing

Entropy may help anesthesiologists assess the effect of certain anesthetics on the patient’s brain³

Accelerate recovery & discharge

Entropy may result in faster emergence from anesthesia and may help clinicians in their goal to increase patient throughput⁴

Decrease drug consumption

Entropy may help save hospitals’ money and support an environmentally conscious anaesthesia⁵

Improve hemodynamic stability

Multiple randomized controlled outcome studies report significant reduction in hemodynamic fluctuations, especially avoidance of hypotension 6,7

Sebel PS, Bowdle TA, Ghoneim MM, et al. The incidence of awareness during anesthesia: a multicenter United States study. Anesth Analg. 2004;99(3):833–839.
DOI: 10.1213/01.ANE.0000130261.90896.6C. Accessed May 20, 2019.

Mashour GA, Avidan MS. Intraoperative awareness: controversies and non-controversies. Br J Anaesth. 2015;115(Suppl 1):i20–i26. DOI: 10.1093/bja/aev034.
Accessed May 20, 2019.

Aimé I, Verroust N, Masson-Lefoll C, Taylor G, Laloë PA, Liu N, Fischler M. Does monitoring bispectral index or spectral entropy reduce sevoflurane use? Anesth Analg. 2006 Dec;103(6):1469-77. doi: 10.1213/01.ane.0000246838.93153.23. PMID: 17122226.

Gruenewald M, Zhou J, Schloemerkemper N, Meybohm P, Weiler N, Tonner PH, Scholz J, Bein B. M-Entropy guidance vs standard practice during
propofol-remifentanil anaesthesia: a randomised controlled trial. Anaesthesia. 2007 Dec;62(12):1224-9. doi: 10.1111/j.1365-2044.2007.05252.x. PMID: 17991257.

Not all products or features are available in all markets. Full product technical specification is available upon request.
Contact a GE HealthCare Representative for more information. Please visit www.gehealthcare.com.
Data subject to change.
© 2024 GE HealthCare
GE is a trademark of General Electric Company used under trademark license. All other trademarks are property of their respective owners.
Reproduction in any form is forbidden without prior written permission from GE HealthCare. Nothing in this material should be used to diagnose or treat any disease or condition. Readers must consult a healthcare professional.

JB06875XX-1 03/2024

Entropy:
A key measurement for personalized anesthesia

Intraoperative awareness facts

26,000 cases

of intraoperative awareness in the U.S. per year and 400,000 globally¹

Experience of awareness with explicit recall of surgical events can potentially lead to post-traumatic stress disorder (PTSD)²

Entropy to assess depth of anesthesia

Entropy use is associated with a 30% reduction in Sevoflurane/ Isoflurane and a 15% reduction in Propofol 4,5,6

Studies have shown that when caring for adults, using Entropy may help hospitals…

Avoid UNDER and OVER dosing

Entropy may help anesthesiologists assess the effect of certain anesthetics on the patient’s brain³

Decrease drug consumption

Entropy may help save hospitals’ money and support an environmentally conscious anaesthesia⁵

Accelerate recovery & discharge

Entropy may result in faster emergence from anesthesia and may help clinicians in their goal to increase patient throughput⁴

Improve hemodynamic stability

Multiple randomized controlled outcome studies report significant reduction in hemodynamic fluctuations, especially avoidance of hypotension 6,7

Mashour GA, Avidan MS. Intraoperative awareness: controversies and non-controversies. Br J Anaesth. 2015;115(Suppl 1):i20–i26. DOI: 10.1093/bja/aev034. Accessed May 20, 2019.

Aimé I, Verroust N, Masson-Lefoll C, Taylor G, Laloë PA, Liu N, Fischler M. Does monitoring bispectral index or spectral entropy reduce sevoflurane use? Anesth Analg. 2006 Dec;103(6):1469-77. doi: 10.1213/01.ane.0000246838.93153.23. PMID: 17122226.

Not all products or features are available in all markets. Full product technical specification is available upon request.
Contact a GE HealthCare Representative for more information. Please visit www.gehealthcare.com.
Data subject to change.
© 2024 GE HealthCare
GE is a trademark of General Electric Company used under trademark license. All other trademarks are property of their respective owners.
Reproduction in any form is forbidden without prior written permission from GE HealthCare. Nothing in this material should be used to diagnose or treat any disease or condition. Readers must consult a healthcare professional.

JB06875XX-1 03/2024

Entropy: A key measurement for personalized anesthesia

Intraoperative awareness facts

26,000 cases

of intraoperative awareness in the U.S. per year
and 400,000 globally¹

Experience of awareness with explicit recall of surgical events can potentially lead to post-traumatic stress disorder (PTSD)²

Entropy to assess depth of anesthesia

Entropy use is associated with a 30% reduction in Sevoflurane/ Isoflurane and a 15% reduction in Propofol 4,5,6

Studies have shown that when caring for adults, using Entropy may help hospitals…

Avoid UNDER and OVER dosing

Entropy may help anesthesiologists assess the effect of certain anesthetics on the patient’s brain³

Accelerate recovery & discharge

Entropy may result in faster emergence from anesthesia and may help clinicians in their goal to increase patient throughput⁴

Decrease drug consumption

Entropy may help save hospitals’ money and support an environmentally conscious anaesthesia⁵

Improve hemodynamic stability

Multiple randomized controlled outcome studies report significant reduction in hemodynamic fluctuations, especially avoidance of hypotension 6,7

Mashour GA, Avidan MS. Intraoperative awareness: controversies and non-controversies. Br J Anaesth. 2015;115(Suppl 1):i20–i26. DOI: 10.1093/bja/aev034. Accessed May 20, 2019.

Aimé I, Verroust N, Masson-Lefoll C, Taylor G, Laloë PA, Liu N, Fischler M. Does monitoring bispectral index or spectral entropy reduce sevoflurane use? Anesth Analg. 2006 Dec;103(6):1469-77. doi: 10.1213/01.ane.0000246838.93153.23. PMID: 17122226.

Not all products or features are available in all markets. Full product technical specification is available upon request.
Contact a GE HealthCare Representative for more information. Please visit www.gehealthcare.com.
Data subject to change.
© 2024 GE HealthCare
GE is a trademark of General Electric Company used under trademark license. All other trademarks are property of their respective owners.
Reproduction in any form is forbidden without prior written permission from GE HealthCare. Nothing in this material should be used to diagnose or treat any disease or condition. Readers must consult a healthcare professional.

JB06875XX-1 03/2024

Entropy: A key measurement for personalized anesthesia

Intraoperative awareness facts

26,000 cases

of intraoperative awareness in the U.S. per year
and 400,000 globally¹

Experience of awareness with explicit recall of surgical events can potentially lead to post-traumatic stress disorder (PTSD)²

Studies have shown that when caring for adults, using Entropy may help hospitals…

Entropy use is associated with a 30% reduction in Sevoflurane/ Isoflurane and a 15% reduction in Propofol 4,5,6

Entropy to assess depth of anesthesia

Accelerate recovery & discharge

Entropy may result in faster emergence from anesthesia and may help clinicians in their goal to increase patient throughput⁴

Improve hemodynamic stability

Multiple randomized controlled outcome studies report significant reduction in hemodynamic fluctuations, especially avoidance of hypotension 6,7

Decrease drug consumption

Entropy may help save hospitals’ money and support an environmentally conscious anaesthesia⁵

Avoid UNDER and OVER dosing

Entropy may help anesthesiologists assess the effect of certain anesthetics on the patient’s brain³

Mashour GA, Avidan MS. Intraoperative awareness: controversies and non-controversies. Br J Anaesth. 2015;115(Suppl 1):i20–i26. DOI: 10.1093/bja/aev034. Accessed May 20, 2019.

Aimé I, Verroust N, Masson-Lefoll C, Taylor G, Laloë PA, Liu N, Fischler M. Does monitoring bispectral index or spectral entropy reduce sevoflurane use? Anesth Analg. 2006 Dec;103(6):1469-77. doi: 10.1213/01.ane.0000246838.93153.23. PMID: 17122226.

Not all products or features are available in all markets. Full product technical specification is available upon request.
Contact a GE HealthCare Representative for more information. Please visit www.gehealthcare.com.
Data subject to change.
© 2024 GE HealthCare
GE is a trademark of General Electric Company used under trademark license. All other trademarks are property of their respective owners.
Reproduction in any form is forbidden without prior written permission from GE HealthCare. Nothing in this material should be used to diagnose or treat any disease or condition. Readers must consult a healthcare professional.

JB06875XX-1 03/2024